§ 270 Fifth Edition
Thus two drops of the fresh vegetable juice mingled with equal parts of alcohol are diluted with ninety-eight drops of alcohol and potentized by means of two succussions, whereby the first development of power is formed and this process is repeated through twenty-nine more phials, each of which is filled three-quarters full with ninety-nine drops of alcohol, and each succeeding phial is to be provided with one drop from the preceding phial (which has already been shaken twice) and is in its turn twice shaken,1 and in the same manner at last the thirtieth development of power (potentized decillionth dilution X) which is the one most generally used.1 In order to maintain a fixed and measured standard for developing the power of liquid medicines, multiplied experience and careful observation have led me to adopt two succussions for each phial, in preference to the greater number formerly employed (by which the medicines were too highly potentized). There are, however, homoeopathists who carry about with them on their visits to patients homoeopathic medicines in the fluid state, and who yet assert that they do not become more highly potentized in the course of time, but they thereby show their want of ability to observe correctly. I discovered a grain of soda in half an once of water mixed with alcohol in a phial, which was thereby filled two-thirds full, and shook this solution continuously for half an hour, and this fluid was in potency and energy equal to the thirtieth development of power.
§ 270 Sixth Edition
In order to best obtain this development of power, a small part of the substance to be dynamized, say one grain, is triturated for three hours with three times one hundred grains sugar of milk according to the method described below1 up to the one-millionth part in powder form. For reasons given below (b) one grain of this powder is dissolved in 500 drops of a mixture of one part of alcohol and four parts of distilled water, of which one drop is put in a vial. To this are added 100 drops of pure alcohol2 and given one hundred strong succussions with the hand against a hard but elastic body.3 This is the medicine in the first degree of dynamization with which small sugar globules4 may then be moistened5 and quickly spread on blotting paper to dry and kept in a well-corked vial with the sign of (I) degree of potency. Only one6 globule of this is taken for further dynamization, put in a second new vial (with a drop a water in order to dissolve it) and then with 100 powerful succussions.With this alcoholic medicinal fluid globules are again moistened, spread upon blotting paper and dried quickly, put into a well-stoppered vial and protected from heat and sun light and given the sign (II) of the second potency. And in this way the process is continued until the twenty-ninth is reached. Then with 100 drops of alcohol by means of 100 succussions, an alcoholic medicinal fluid is formed with which the thirtieth dynamization degree is given to properly moistened and dried sugar globules.
By means of this manipulation of crude drugs are produced preparations which only in this way reach the full capacity to forcibly influence the suffering parts of the sick organism. In this way, by means of similar artificial morbid affection, the influence of the natural disease on the life principle present within is neutralized. By means of this mechanical procedure, provided it is carried out regularly according to the above teaching, a change is effected in the given drug, which in its crude state shows itself only as material, at times as unmedicinal material but by means of such higher and higher dynamization, it is changed and subtlized at last into spirit-like7 medicinal power, which, indeed, in itself does not fall within our senses but for which the medicinally prepared globule, dry, but more so when dissolved in water, becomes the carrier, and in this condition, manifests the healing power of this invisible force in the sick body.
1 One-third of one hundred grains sugar of milk is put in a glazed porcelain mortar, the bottom dulled previously by rubbing it with fine, moist sand. Upon this powder is put one grain of the powdered drug to be triturated (one drop of quicksilver, petroleum, etc.). The sugar of milk used for dynamization must be of that special pure quality that is crystallized on strings and comes to us in the shape of long bars. For a moment the medicines and powder are mixed with a porcelain spatula and triturated rather strongly, six to seven minutes, with the pestle rubbed dull, then the mass is scraped from the bottom of the mortar and from the pestle for three to four minutes, in order to make it homogeneous. This is followed by triturating it in the same way 6 - 7 minutes without adding anything more and again scraping 3 - 4 minutes from what adhered to the mortar and pestle. The second third of the sugar of milk is now added, mixed with the spatula and again triturated 6 - 7 minutes, followed by the scraping for 3 - 4 minutes and trituration without further addition for 6 - 7 minutes. The last third of sugar of milk is then added, mixed with the spatula and triturated as before 6 -7 minutes with most careful scraping together. The powder thus prepared is put in a vial, well corked, protected from direct sunlight to which the name of the substance and the designation of the first product marked /100 is given. In order to raise this product to /10000, one grain of the powdered /100 is mixed with the third part of 100 grains of powdered sugar of milk and then proceed as before, but every third must be carefully triturated twice thoroughly each time for 6 -7 minutes and scraped together 3 -4 minutes before the second and last third of sugar of milk is added. After each third, the same procedure is taken. When all is finished, the powder is put in a well corked vial and labelled /10000, i.e., (I), each grain containing 1/1,000,000 the original substance. Accordingly, such a trituration of the three degrees requires six times six to seven minutes for triturating and six times 3 -4 minutes for scraping, thus one hour for every degree. After one hour such trituration of the first degree, each grain will contain 1/000; of the second 1/10,000; and in the third 1/1,000,000 of the drug used.* Mortar and spatula must be cleaned well before they are used for another medicine. Washed first with warm water and dried, both mortar and pestle, as well as spatula are then put in a kettle of boiling water for half an hour. precaution might be used to such an extent as to put these utensils on a coal fire exposed to a glowing heat.
* These are the three degrees of the dry powder trituration, which if carried out correctly, will effect a good beginning for the dynamization of the medicinal substance.
2 The vial used for potentizing is filled two-thirds full.
3 Perhaps on a leather bound book.
4 They are prepared under supervision by the confectioner from starch and sugar and the small globules freed from fine dusty parts by passing them through a sieve. Then they are put through a strainer that will permit only 100 to pass through weighing one grain, the most serviceable size for the needs of a homoeopathic physician.
5 A small cylindrical vessel shaped like a thimble, made of glass, porcelain or silver, with a small opening at the bottom in which the globules are put to be medicated. They are moistened with some of the dynamized medicinal alcohol, stirred and poured out on blotting paper, in order to dry them quickly.
6 According to first directions, one drop of the liquid of a lower potency was to be taken to 100 drops of alcohol for higher potentiation. This proportion of the medicine of attenuation to the medicine that is to be dynamized (100:1) was found altogether too limited to develop thoroughly and to a high degree the power of the medicine by means of a number of such succussions without specially using great force of which wearisome experiments have convinced me.
But if only one such globule be taken, of which 100 weigh one grain, and dynamize it with 100 drops of alcohol, the proportion of 1 to 50,000 and even greater will be had, for 500 such globules can hardly absorb one drop, for their saturation. With this disproportionate higher ratio between medicine and diluting medium many successive strokes of the vial filled two-thirds with alcohol can produce a much greater development of power. But with so small a diluting medium as 100 to 1 of the medicine, if many succussions by means of a powerful machine are forced into it, medicines are then developed which, especially in the higher degrees of dynamization, act almost immediately, but with furious, even dangerous violence, especially in weakly patients, without having a lasting, mild reaction of the vital principle. But the method described by me, on the contrary, produces medicines of highest development of power and mildest action, which, however, if well chosen, touches all suffering parts curatively.* In acute fevers, the small doses of the lowest dynamization degrees of these thus perfected medicinal preparations, even of medicines of long continued action (for instance, belladonna) may be repeated in short intervals. In the treatment of chronic diseases, it is best to begin with the lowest degrees of dynamization and when necessary advance to higher, even more powerful but mildly acting degrees.
* In very rare cases, notwithstanding almost full recovery of health and with good vital strength, an old annoying local trouble continuing undisturbed it is wholly permitted and even indispensably necessary, to administer in increasing doses the homoeopathic remedy that has proved itself efficacious but potenized to a very high degree by means of many succussions by hand. Such a local disease will often then disappear in a wonderful way.
7 This assertion will not appear improbable, if one considers that by means of this method of dynamization (the preparations thus produced, I have found after many laborious experiments and counter-experiments, to be the most powerful and at the same time mildest in action, i.e., as the most perfected) the material part of the medicine is lessened with each degree of dynamization 50,000 times yet incredibly increased in power, so that the further dynamization of 125 and 18 ciphers reaches only the third degree of dynamization. The thirtieth thus progressively prepared would give a fraction almost impossible to be expressed in numbers. It becomes uncommonly evident that the material part by means of such dynamization (development of its true, inner medicinal essence) will ultimately dissolve into its individual spirit-like, (conceptual) essence. In its crude state therefore, it may be considered to consist really only of this underdeveloped conceptual essence.
§ 271 Fifth Edition
All other substances adapted for medicinal use - except sulphur, which has of late years been only employed in the form of a highly diluted (X) tincture - as pure or oxidized and sulphuretted metals and other minerals, petroleum, phosphorus, as also parts and juices of plants that can only be obtained in the dry state, animal substances, neutral salts, etc., all these are first to be potentized by trituration for three hours, up to the millionfold pulverulent attenuation, and of this one grain is to be dissolved, and brought to the thirtieth development of power through twenty-seven attenuating phials, in the same manner as the vegetable juices.11 As is still more circumstantially described in the prefaces to Arsenic and Pulsatilla in the Materia Medica Pura.
§ 271 Sixth Edition
If the physician prepares his homoeopathic medicines himself, as he should reasonably do in order to save men from sickness,1 he may use the fresh plant itself, as but little of the crude article is required, if he does not need the expressed juice perhaps for purposes of healing. He takes a few grains in a mortar and with 100 grains sugar of milk three distinct times brings them to the one-millionth trituration (§ 270) before further potentizing of a small portion of this by means of shaking is undertaken, a procedure to be observed also with the rest of crude drugs of either dry or oily nature.1 Until the State, in the future, after having attained insight into the indispensability of perfectly prepared homoeopathic medicines, will have them manufactured by a competent impartial person, in order to give them free of charge to homoeopathic physicians trained in homoeopathic hospitals, who have been examined theoretically and practically, and thus legally qualified. The physician may then become convinced of these divine tools for purposes of healing, but also to give them free of charge to his patients - rich and poor.
§ 272 Fifth Edition
In no case is it requisite to administer more than one single, simple medicinal substance at one time.11 Some homoeopathists have made the experiment, in cases where they deemed one remedy homoeopathically suitable for one portion of the symptoms of a case of disease, and a second for another portion, of administering both remedies at the same time; but I earnestly deprecate such a hazardous experiment, which can never be necessary, though it may sometimes seem to be of use.
§ 272 Sixth Edition
Such a globule,1 placed dry upon the tongue, is one of the smallest doses for a moderate recent case of illness. Here but few nerves are touched by the medicine. A similar globule, crushed with some sugar of milk and dissolved in a good deal of water (§ 247) and stirred well before every administration will produce a far more powerful medicine for the use of several days. Every dose, no matter how minute, touches, on the contrary, many nerves.1 These globules (§ 270) retain their medicinal virtue for many years, if protected against sunlight and heat.
§ 273 Fifth Edition
It is not conceivable how the slightest dubiety could exist as to whether it was more consistent with nature and more rational to prescribe a single well-known medicine at one time in a disease, or a mixture of several differently acting drugs.§ 273 Sixth Edition
In no case under treatment is it necessary and therefore not permissible to administer to a patient more than one single, simple medicinal substance at one time. It is inconceivable how the slightest doubt could exist as to whether it was more consistent with nature and more rational to prescribe a single, simple1 medicine at one time in a disease or a mixture of several differently acting drugs. It is absolutely not allowed in homoeopathy, the one true, simple and natural art of healing, to give the patient at one time two different medicinal substance.1 Two substances, opposite to each other, united into neutral Natrum and middle salts by chemical affinity in unchangeable proportions, as well as sulphurated metals found in the earth and those produced by technical art in constant combining proportions of sulphur and alkaline salts and earths, for instance (natrum sulph. and calcarea sulph.) as well as those ethers produced by distillation of alcohol and acids may together with phosphorus be considered as simple medicinal substances by the homoeopathic physician and used for patients. On the other hand, those extracts obtained by means of acids of the so-called alkaloids of plants, are exposed to great variety in their preparation (for instance, chinin, strychnine, morphine), and can, therefore, not be accepted by the homoeopathic physician as simple medicines, always the same, especially as he possesses, in the plants themselves, in their natural state (Peruvian bark, nux vomica, opium) every quality necessary for healing. Moreover, the alkaloids are not the only constituents of the plants.
As the true physician finds in simple medicines, administered singly and uncombined, all that he can possibly desire (artificial disease-force which are able by homoeopathic power completely to overpower, extinguish, and permanently cure natural diseases), he will, mindful of the wise maxim that it is wrong to attempt to employ complex means when simple means suffice, never think of giving as a remedy any but a single, simple medicinal substance; for these reasons also, because even though the simple medicines were thoroughly proved with respect to their pure peculiar effects on the unimpaired healthy state of man, it is yet impossible to foresee how two and more medicinal substances might, when compounded, hinder and alter each other's actions on the human body; and because, on the other hand, a simple medicinal substance when used in diseases, the totality of whose symptoms is accurately known, renders efficient aid by itself alone, if it be homoeopathically selected; and supposing the worst case to happen, that it was not chosen in strict conformity to similarity of symptoms, and therefore does no good, it is yet so far useful that it promoted our knowledge of therapeutic agents, because, by the new symptoms excited by it in such a case, those symptoms which this medicinal substance had already shown in experiments on the healthy human body are confirmed, an advantage that is lost by the employment of all compound remedies.1
1 When the rational physician has chosen the perfectly homoeopathic medicine for the well-considered case of disease and administered it internally, he will leave to irrational allopathic routine the practice of giving drinks or fomentations of different plants, of injecting medicated glysters and of rubbing in this or the other ointment.
The suitableness of a medicine for any given case of disease does not depend on its accurate homoeopathic selection alone, but likewise on the proper size, or rather smallness, of the dose. If we give too strong a dose of a medicine which may have been even quite homoeopathically chosen for the morbid state before us, it must, notwithstanding the inherent beneficial character of its nature, prove injurious by its mere magnitude, and by the unnecessary, too strong impression which, by virtue of its homoeopathic similarity of action, it makes upon the vital force which it attacks and, through the vital force, upon those parts of the organism which are the most sensitive, and are already most affected by the natural disease.
§ 276 Fifth Edition
For this reason, a medicine, even though it may be homoeopathically suited to the case of disease, does harm in every dose that is too large, the more harm the larger the dose, and by the magnitude of the dose it does more harm the greater its homoeopathicity and the higher the potency1 selected, and it does much more injury than any equally large dose of a medicine that is unhomoeopathic, and in no respect adapted (allopathic) to the morbid state; for in the former case the so-called homoeopathic aggravation (§§157-160) - that is to say, the very analogous medicinal disease produced by the vital force stirred up by the excessively large dose of medicine, in the parts of the organism that are most suffering and most irritated by the original disease - which medicinal disease, had it been of appropriate intensity, would have gently effected a cure - rises to an injurious height;2 the patient, to be sure, no longer suffers from the original disease, for that has been homoeopathically eradicated, but he suffers all the more from the excessive medicinal disease and from useless exhaustion of his strength.1 The praise bestowed of late years by some few homoeopathists on the larger doses is owing to this, either that they chose low dynamizations of the medicines to be administered, as I myself used to do twenty years ago, from not knowing any better, or that the medicines selected were not perfectly homoeopathic.
2 See note to §246
§ 276 Sixth Edition
For this reason, a medicine, even though it may be homoeopathically suited to the case of disease, does harm in every dose that is too large, the more harm the larger the dose, and by the magnitude of the dose and in strong doses' it does more harm the greater its homoeopathicity and the higher the potency1 selected, and it does much more injury than any equally large dose of a medicine that is unhomoeopathic, and in no respect adapted to the morbid state (allopathic).Too large doses of an accurately chosen homoeopathic medicine, and especially when frequently repeated, bring about much trouble as a rule. They put the patient not seldom in danger of life or make this disease almost incurable. They do indeed extinguish the natural disease so far as the sensation of the life principle is concerned and the patient no longer suffers from the original disease from the moment the too strong dose of the homoeopathic medicine acted upon him but he is in consequence more ill with the similar but more violent medicinal disease which is most difficult to destroy.2
1 The praise bestowed of late years by some homoeopathists on the larger doses is owing to this, either that they chose low dynamizations of the medicine to be administered (as I myself used to do twenty years ago, from nor knowing any better), or that the medicines selected were not homoeopathic and imperfectly prepared by their manufacturers.
2 Thus, the continuous use of aggressive allopathic large doses of mercurials against syphilis develops almost incurable maladies, when yet one or several doses of a mild but active mercurial preparation would certainly have radically cured in a few days the whole venereal disease, together with the chancre, provided it had not been destroyed by external measures (as is always done by allopathy). In the same way, the allopath gives Peruvian bark and quinine in intermittent fever daily in very large doses, where they are correctly indicated and where one very small dose of a highly potentized China would unfailingly help (in marsh intermittents and even in persons who were not affected by any evident psoric disease). A chronic China malady (coupled at the same time with the development of psora) is produced, which, if it dose not gradually kill the patient by damaging the internal important vital organs, especially spleen and liver, will put him, nevertheless suffering for years in a sad state of health. A homoeopathic antidote for such a misfortune produced by abuse of large doses of homoeopathic remedies is hardly conceivable.
For the same reason, and because a medicine, provided the dose of it was sufficiently small, is all the more salutary and almost marvellously efficacious the more accurately homoeopathic its selection has been, a medicine whose selection has been accurately homoeopathic must be all the more salutary the more its dose is reduced to the degree of minuteness appropriate for a gentle remedial effect.
§ 278 Fifth Edition
Here the question arises, what is this most suitable degree of minuteness for sure and gentle remedial effect; how small, in other words, must be the dose of each individual medicine, homoeopathically selected for a case of disease, to effect the best cure? To solve this problem, and to determine for every particular medicine, what dose of it will suffice for homoeopathic therapeutic purposes and yet be so minute that the gentlest and most rapid cure may be thereby obtained - to solve this problem is, as may easily be conceived, not the work off theoretical speculation; not by fine-spun reasoning, not by specious sophistry can we expect to obtain the solution of this problem. Pure experiment, careful observation, and accurate experience can alone determine this; and it were absurd to adduce the large doses of unsuitable (allopathic) medicines of the old system, which do not touch the diseased side of the organism homoeopathically, but only attack the parts unaffected by the disease, in opposition to what pure experience pronounces respecting the smallness of the doses required for homoeopathic cures.§ 278 Sixth Edition
Here the question arises, what is this most suitable degree of minuteness for sure and gentle remedial effect; how small, in other words, must be the dose of each individual medicine, homoeopathically selected for a case of disease, to effect the best cure? To solve this problem, and to determine for every particular medicine, what dose of it will suffice for homoeopathic therapeutic purposes and yet be so minute that the gentlest and most rapid cure may be thereby obtained - to solve this problem is, as may easily be conceived, not the work off theoretical speculation; not by fine-spun reasoning, not by specious sophistry can we expect to obtain the solution of this problem. It is just as impossible as to tabulate in advance all imaginable cases. Pure experiment, careful observation of the sensitiveness of each patient, and accurate experience can alone determine this; and it were absurd to adduce the large doses of unsuitable (allopathic) medicines of the old system, which do not touch the diseased side of the organism homoeopathically, but only attack the parts unaffected by the disease, in opposition to what pure experience pronounces respecting the smallness of the doses required for homoeopathic cures.§ 279 Fifth Edition
This pure experience shows UNIVERSALLY, that if the disease do not manifestly depend on a considerable deterioration of an important viscus (even though it belong to the chronic and complicated diseases), and if during the treatment all other alien medicinal influences are kept away from the patients, the dose of the homoeopathically selected remedy can never be prepared so small that it shall not be stronger than the natural disease, and shall not be able to overpower, extinguish and cure it, at least in part as long as it is capable of causing some, though but a slight preponderance of its own symptoms over those of the disease resembling it (slight homoeopathic aggravation, (§§ 157-160) immediately after its ingestion.§ 279 Sixth Edition
This pure experience shows UNIVERSALLY, that if the disease do not manifestly depend on a considerable deterioration of an important viscus (even though it belong to the chronic and complicated diseases), and if during the treatment all other alien medicinal influences are kept away from the patients, the dose of the homoeopathically selected and highly potentized remedy for the beginning of treatment of an important, especially chronic disease can never be prepared so small that it shall not be stronger than the natural disease and shall not be able to overpower it, at least in part and extinguish it from the sensation of the principle of life and thus make a beginning of a cure.
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